Completed diagnostic tests projects
Early detection is important to reduce transmission, but also because it reduces the risk of permanent impairments. LRI supports studies which aim to develop and test new assays for diagnosis of disease and infection.
qPCR in household contact monitoring
Laboratório de Hanesíase Fundação Oswaldo Cruz/ FIOCRUZ (Brazil)
There are no diagnostic tests that could predict whether or not a “contact” will develop the disease. This project investigated the possible use of M.leprae DNA detection as a early detection method in over 1600 household contacts of leprosy patients. Results available
Novel immunodiagnostic tools
Erasmus MC, University Medical Center Rotterdam (Netherlands)
This study aimed to identify compounds of the immune system that are characteristic for the occurrence of leprosy and may differentiate between persons affected by leprosy, their contacts and healthy controls. Such compounds are called leprosy-specific biomarkers.